Anti-tumor immunostimulatory effect of heat-killed tumor cells

heat-treated tumor lysate loaded lymphoide dendritic cells: evaluation of cytotoxic effect in the tumor bearing mice

objective: dendritic cells (dcs) are essential for the activation and polarization of t cells during an adaptive immune response. in this research we investigated the effect of the lymphoide dcs pulsed with heat-treated tumor lysate (htl) as a vaccine in tumor immunotherapy. materials and methods: the balb/c mice were injected subcutaneously in the right flank with wehi-164 fibrosarcoma cells ...

Tumor-Specific Immune Responses and Present Their Antigens to Elicit Dendritic Cells Capture Killed Tumor Cells

Anti-Tumor Effect of Doxycycline on Glioblastoma Cells

Anti-angiogenic, Anti-tumor and Immunostimulatory Effects of a Non-toxic Plant Extract (pgm)

Recruitment of new blood vessels plays a crucial role in tumor survival and growth. Several agents that act as angiogenesis inhibitors are currently being investigated as anti-tumor agents. Proteoglycan extract (PGM) was tested for anti-angiogenic, immunostimulatory, and anti-neoplastic activity. PGM is a non-toxic extract of the ubiquitous plant, Convolvulus arvensis. In the chicken egg chorio...

Effect of Heat-killed Saccharomyces cerevisiae on Growth Rate and Apoptosis in Colorectal Cancer Cells

Background and purpose: Colorectal cancer ( CRC ) is highly prevalent and conventional therapies are associated with side effects, therefore, application of novel complementary treatment such as probiotics (especially Saccharomyces cerevisiae) is necessary. The aim of this study was to investigate the effect of heat-killed form of S.cerevisiae on growing rate and apoptosis (expression levels of...